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Outside of the word ‘Ma’am’ there is another word — the ‘F-A-T’ word that I despise quite vehemently… it’s been refreshing to be rid of at least one of those words this week!

An interesting study…
This study shows that serum brain-derived neurotophic factor (BDNF) is significantly lower in women with anorexia nervosa (AN) compared with women without an eating disorder and women recovered from AN. While recovery from AN is difficult to define, BDNF may emerge as a useful biomarker of AN and of recovery from AN.
Finding biomarkers for AN and recovery from AN can help improve diagnostic accuracy and help better identify individuals who have recovered from AN. BDNF polymorphisms have not only previously been associated with AN {1}, but the BDNF-specific receptor neurotrophic tyrosine kinase receptor type 2 has also been associated with temperament characteristics and low BMI in individuals with eating disorders {2}. The current study evaluated serum BDNF levels in women with AN (n=29), women without an eating disorder (n=28) and women recovered from AN for 1 or more years (n=18). In addition, set-shifting ability was also evaluated in all 3 groups using the Wisconsin Card Sorting Task (WCST). Age was similar among all three groups, and women with AN and recovered women did not differ in lowest lifetime BMI. Women with AN had lower serum BDNF than controls and recovered women. Overall, there was a positive association between BDNF and BMI. BDNF was inversely correlated with the eating concerns, shape concerns, weight concerns, and global scale on the Eating Disorder Examination Questionnaire and on the depression and anxiety sections of the Hospital Anxiety and Depression Scale. Women with AN made more mistakes on the WCST than control women, but BDNF level was not associated with performance on the WCST. Set-shifting was not impaired in individuals recovered from AN. The current study excluded healthy control women with a BMI below 19 or over 26 thereby excluding constitutionally thin and obese women. It is plausible that BDNF is related more to BMI or the starvation state than to AN per se. However, the relationship between BDNF and BMI is unclear as the results from one study indicate lower levels of BDNF in morbidly obese individuals compared with obese individuals {3}. Including constitutionally lean and obese women in future studies may help clarify the relationship among BDNF, BMI, and AN. BDNF may be a useful biomarker in the underweight AN state and in indexing recovery from AN. However, it is important to first ensure that BDNF is in fact associated with AN and not strictly BMI or other indices of starvation.
References: {1} Ribases et al. Mol Psychiatry 2003, 8:745-51 ]. {2} Ribases et al. Mol Psychiatry 2005, 10:851-60 ]. {3} Bullo et al. Eur J Endocrinol 2007, 157:303-10 ].
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When you begin to touch your heart or let your heart be touched, you begin to discover that it’s bottomless, that it doesn’t have any resolution, that this heart is huge, vast, and limitless. You begin to discover how much warmth and gentleness is there, as well as how much space.


The National Eating Disorders Association-NEDA has issued a Call for Proposals for the September ‘09 Conference sagaciously titled: Reshaping Our Future: A Vision for Recovery, Research, Attitudes and Action!
The goals of this conference are:
- Help family members, treatment professionals, health educators and activists to connect and share useful and supportive information that can be transformed into action.
- Familiarize attendees with the latest developments in the field of eating disorders and the implications of this new knowledge for prevention and treatment.
- Reduce the associated stigma of eating disorders and generate awareness about the realities of the illnesses by educating conference attendees, the media and, in turn, the general public, policymakers and opinion leaders.
- Provide a national convening to promote inclusiveness, enthusiasm, energy, optimism and a vision of hope for all conference attendees.
Workshop presenters can have a focus within the areas of family, treatment, special issues, outreach and education. The conference will be held in Minneapolis, Minnesota September 10-12th, and the deadline for conference committee consideration on submissions is Wednesday, March 25th.
For further information contact Director of Programs-Laurie Vanderbloom info@nationaleatingdisorders.org – (206)382.3587.

… but we’ll happily settle.
When he speaks,
The air, a chartered libertine, is still.
Henry V, 1.1








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